Background Intratumoral heterogeneity (ITH) and subclonal antigen expression blunt antitumor immunity and are associated with poor responses to immune-checkpoint blockade immunotherapy (ICB) in patients with cancer.The underlying mechanisms however thus far remained elusive, preventing the design of novel treatment approaches for patients with high
The paper shows the results of assessing the possibilities of computational fluid dynamics for predicting the motions of a ship with a moonpool and vertical water motions in a moonpool in regular head waves with a zero ship speed.A moonpool is a well which is used in different types of ships such as cable laying, drill and FPSO, survey, research Fe
A male in his 60s presented with transient ischemic attacks 5 years after Western Pads Tough 1 aortic arch branch graft repair for type A aortic dissection.Computed tomographic angiography demonstrated 80% stenosis of the brachiocephalic artery close to the origins of the right common carotid and subclavian arteries.The case was reviewed at our mul
Article presents the results of research and development works implemented by international partnership in the frame of Erasmus +Programme.Ecomentor Project refers to the Jukeboxes process of mentoring in continuing vocational education, especially work-based learning.International team of researchers developed the unified competence EARTHPASTE LEM